Buprenorphine in the Treatment of Opioid Dependence

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Applied Pharmacology: Acute Buprenorphine Effects

Jasinski DR, Pevnick JS, and Griffith JD. Human pharmacology and abuse potential of the analgesic buprenorphine. Archives of General Psychiatry (35):501–516, 1978.

Jasinski DR, Fudala PJ, and Johnson RE. Sublingual versus subcutaneous buprenorphine in opiate abusers. Clinical Pharmacology and Therapeutics (45):513–519, 1989.

Pickworth WB, Johnson RE, Holicky BA, and Cone EJ. Subjective and physiologic effects of intravenous buprenorphine in humans. Clinical Pharmacology and Therapeutics (53):570–576, 1993.

Schuh KJ, Walsh SL, Bigelow GE, Preston KL, and Stitzer ML. Buprenorphine, morphine, and naloxone effects during ascending morphine maintenance in humans. Journal of Pharmacology and Experimental Therapeutics (278):836–846, 1996.

Strain EC, Preston KL, Liebson IA, and Bigelow GE. Acute effects of buprenorphine, hydromorphone, and naloxone in methadone-maintained volunteers. Journal of Pharmacology and Experimental Therapeutics (261):985–993, 1992.

Strain EC, Preston KL Liebson IA, and Bigelow GE. Buprenorphine effects in methadone-maintained volunteers: Effects at 2 hours after methadone. Journal of Pharmacology and Experimental Therapeutics (272):628–638, 1995.

Walsh SL, Preston KL, Stitzer ML, Cone EJ, and Bigelow GE. Clinical pharmacology of buprenorphine: Ceiling effects at high doses. Clinical Pharmacology and Therapeutics (55):569–580, 1994.

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